A man has been killed and another is fighting for life after a car allegedly swerved into fans outside a gaming convention in Melbourne.

The grey Toyota is understood to have mounted a curb where three men were standing outside the Supanova Comic Con and Gaming event at the Melbourne Showgrounds, just after 5pm on Saturday.

The car struck the trio who were on their way home from the event, with one who is yet to be identified dying at the scene, and another rushed to hospital with life-threatening injuries. Both are in their 20s.

Victoria Police Detective Inspector Craig McEvoy confirmed a 33-year-old Werribee man, who was the driver, was arrested at the scene by an off-duty cop.

He remains under police guard in hospital and Mr McEvoy said he was ‘well known to police’.

‘They (the three men) were on their way home and unfortunately they have been mowed down and struck just outside the Gates of Flemington Showgrounds,’ Mr McEvoy told reporters.

‘We’re still yet to determine if drugs, alcohol, speed are involved, but that will form part of our investigation. Nothing suggests at this point in time it’s medically related.’

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The grey Toyota is understood to have mounted a curb where three men were standing outside the Supanova Comic Con and Gaming event at the Melbourne Showgrounds, just after 5pm on Saturday

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Police have arrested a man after a Toyota allegedly swerved into people outside a convention in Melbourne

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The incident happened at the Melbourne Showgrounds, killing one and seriously injuring another

A witness, Tom, was leaving the convention with his wife and daughter when they saw a Toyota allegedly speed past them on Langs Road.

‘I heard a screech and a guy (allegedly) mounted the kerb at an erratic speed, hit a couple people,’ Tom told The Age.

Tom then said the car did a U-turn before driving back down the street.

The driver then stalled, according to the witness, who attempted to perform a citizen’s arrest.

‘He was erratic. ‘I said, “you’re not going anywhere mate”,’ Tom told the publication.

Victoria Police quickly arrived and arrested the driver.

Tom said his wife, who is a paramedic, worked on a victim who was allegedly hit by the car for 20 minutes before ambulances arrived.

‘He couldn’t move, but he was breathing,’ Tom said.

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The driver of the Toyota remains under police guard in hospital

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A number of SES tents were set up at the scene

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The grey Toyota is understood to have mounted a curb where fans were standing outside the Supanova Comic Con and Gaming event at the Melbourne Showgrounds, just after 5pm on Saturday

Police remain at the scene and investigations are ongoing.

SES tents have meanwhile been set up.

Victorian MP Jason Wood shared the news on social media.

‘My thoughts and prayers go out to the victims and their loved ones. This is very sad,’ Wood, a former cop and member of the Liberal party wrote.

Supanova is a convention about science fiction and fantasy TV shows, comic books, gaming and collectables. Police are urging anyone who witnessed the incident, have CCTV or dashcam vision or have any information, to contact Crime Stoppers.

The Supanova Comic Con and Gaming event posted a statement on Facebook, sharing its condolences to those impacted by the incident.

‘We here at Supanova Comic Con & Gaming are deeply saddened and distressed by the incident that occurred outside the Melbourne Showgrounds this evening,’ the statement read.

‘Our thoughts and prayers go out to all those affected by the unspeakable tragedy that has happened on our doorstep.’

The convention will continue as planned tomorrow.

‘Supanova will continue to support all Supa-Fans that come through our doors tomorrow morning, and we will be holding a minute’s silence in sympathy and solidarity of the affected families and friends at 10am before opening our doors to our event,’ the statement said.