Calling all Doc Martin fans! The US remake of the hit ITV comedy-drama has officially arrived in the UK following its US debut earlier this year.

Best Medicine stars The Good Wife‘s Josh Charles as Martin Best, a physician who trades his high-flying surgical career in Boston for a quiet life in a small coastal town. However, between his severe blood phobia and a town brimming with quirky characters, Martin finds adjusting to his new surroundings quite a challenge.

© FOX via Getty Images
Josh Charles stars as Dr Martin Best

The series was a runaway hit in the US, amassing 15 million regular viewers by its finale. This charming, cosy medical drama is perfect for anyone seeking wholesome, escapist television. Fans of the original will also be delighted by a cameo from Martin Clunes, who captured hearts as the original grumpy yet lovable GP.

Read on for everything you need to know about the show.

WATCH: A first look at Best Medicine, starring Josh Charles

What is Best Medicine about?

Hailed by viewers as ‘fantastic’ and ‘delightful,’ the series follows Dr. Martin Best as he seeks a fresh start in the coastal fishing town of Port Wenn, Maine. While he hopes for a simple life running his new private practice, the town’s eccentric residents have other plans.

The synopsis continues: “Soon he’s introduced to Port Wenn’s community, filled with quirky but loving characters with no end of ailments for him to figure out and diagnose. However, as someone who is quite introverted and likes to keep himself to himself, he struggles with the adjustment.

© Francisco Roman/FOX
Abigail Spencer plays Louisa Gavin

“He’s also got a huge blood phobia – which doesn’t help his abilities as a doctor who may need to tend to wounds from time to time.

“But behind his brusque attitude and no-nonsense approach to a bedside manner, Dr Martin hides his own personal pain that he is hiding from the world which explains why he is the way he is.

© Francisco Roman/FOX
Martin Clunes appears as Martin’s dad, Robert

“Will this little town bring him out of his shell?”

Who stars in Best Medicine?

Josh Charles (The Good Wife, The Handmaid’s Tale) leads the show as Dr. Martin Best.

He’s joined by Abigail Spencer (Grey’s Anatomy) as Louisa Gavin, Josh Segarra (Abbott Elementary) as Mark Mylow, Cree (Big Sky) as Elaine Denton and Annie Potts (Pretty In Pink) as Aunt Sarah.

© Jojo Whilden/FOX
The series is now available on Sky and NOW in the UK

Other cast members include Stephen Spinella (American Classic) as Greg Garrison, Jason Veasey (Only Murders In The Building) as George Brady, Carter Shimp (The Holdovers) as Al Large, Alexandra Cica (I Still Hate You) as Harley, John DiMaggio (Perry Mason) as Bert Large, Clea Lewis (American Rust) as Sally Mylow and Didi Conn (Harlan Coben’s Shelter) as Geneva Potter.

Martin Clunes makes a special appearance in episode nine as Josh’s on-screen father, Robert Best.

How to watch Best Medicine

Best Medicine premiered in the UK on 9 June on Sky. The series is available on Sky One and NOW in the UK and airs on Fox in the US.