A UPS plane crashed at Louisville’s international airport, causing an explosion, dangerous plumes of smoke and fire to spread nearly a mile.

At least seven people are dead and 11 injured. There are two people in critical condition and eight with non-life-threatening injuries at UofL hospitals.

Gov. Andy Beshear said he expects those numbers to grow. He also said there were two employees from a nearby auto store who are unaccounted for.

Mayor Craig Greenberg said the first four confirmed deaths were people who were not on the plane.

The FAA said the cargo plane crashed around 5:15 p.m. as it was taking off from SDF, heading toward Daniel K. Inouye International Airport in Honolulu, Hawaii.

UPS said there were three crewmembers on board.

Because of the long trip, the plane was fully fueled, leading to a large fire. It was carrying about 38,000 gallons of fuel. The fire spread easily to nearby facilities, including a large recycling center.

So far, there are no reports of anyone trapped, but more than a dozen entities are on the scene and nearby buildings are being searched.

Fire officials said they are going door-to-door in the immediate area to make sure everyone is accounted for.

The fires from the crash were out as of 11 p.m. Tuesday night.

SDF said the airfield is closed and screening at the TSA security checkpoint is temporarily suspended.

Passengers scheduled to depart from or arrive in SDF Tuesday or Wednesday should closely monitor their flight status.

UPS Worldport is halting operations. Next Day Air sort has been canceled and employees should not report to work Tuesday night.

Beshear said there was no hazardous material on board. However, officials said there are still several businesses affected and there are some hazardous materials there to address.

For safety reasons, LG&E de-energized power lines into a nearby station in light of the crash, which means service for around 290 customers is interrupted. They also isolated a portion of their gas system, impacting more than 90 customers. Officials say these number could change as emergency responders continue to work.

The type of aircraft that crashed is an MD-11. It is 34 years old.

UPS said the National Transportation Safety Board is in charge of the investigation and will be the primary source of information.